Non-enzymatic electrochemical glucose detection. by David John Morrow

Cover of: Non-enzymatic electrochemical glucose detection. | David John Morrow

Published .

Written in English

Read online

Edition Notes

Thesis (Ph. D.)--The Queen"s University of Belfast, 1987.

Book details

The Physical Object
Pagination1 v
ID Numbers
Open LibraryOL19800410M

Download Non-enzymatic electrochemical glucose detection.

Electrochemical Non-Enzymatic Glucose Sensors Article in Analytica chimica acta (1) February with Reads How we measure 'reads'. The calibration plot for the electrochemical response of Ag–PANI/rGO towards glucose was recorded for the range of 50 μM to μM (R 2 = ) with a detection limit of μM and a rapid response time of a few seconds.

These results indicate the significant potential of Ag–PANI/rGO nanocomposites as non-enzymatic glucose : Megha Anantrao Deshmukh, Byeong-Cheol Kang, Tae-Jun Ha. The nickel oxide flower like morphology has shown good electrochemical performances for the oxidation of glucose.

The presented sensing material was able to detected glucose in a wide range of concentration of mM to 8 mM with a high sensitivity ( μmA/mM) and regression coefficient of Glucose sensors have been extensively developed because of their broad applications, especially in diabetes diagnosis.

Up to date, electrochemical enzymatic glucose sensors are commonly used in daily life for glucose detection and commercially successful as glucose-meters because they exhibit excellent selectivity, high reliability, and could be handled under physiological pH Cited by: Electrochemical Non-Enzymatic Glucose Sensors: A Perspective and an Evaluation Article (PDF Available) in International journal of electrochemical science 5(9).

The electrochemical activities of various nanomaterials have been investigated for use in non-enzymatic electrochemical glucose sensors with high sensitivity, selectivity, and long-term stability; these materials include copper oxide [], ferrite [], nickel hydroxide [], Ni foam [], and carbon nanotubes [].However, the high overpotential of glucose oxidation is a problem with Cited by: 6.

The typical commercial electrochemical blood glucose biosensor has a small volume electrochemical cell, utilizes capillary fill and comprises a stable enzyme and electroactive reagents [96]. It detects H 2 O 2 using amperometric detection, providing fast response times (few seconds) within a dynamic sensing range (10– mg/dL) for measuring.

Using the NiO/SCCNT composites, we demonstrated the fabrication of an electrochemical sensor with high sensitivity of μA cm −2 mM −1 and an ultrafast response (Cited by: 1. Glucose sensors using other magnetic particles have been described such as for example mixtures of Fe 3 O 4 nanoparticles with chitosan and glucose oxidase which could be crosslinked onto platinum electrodes.

The nanopar-ticles have a chemistry that mimics peroxidase and leads to the development of a sensor with good sensitivity and largely free from the effect of Cited by: 2.

The sensing area is measured to be enhanced by folds. Actual glucose detections demonstrated that the proposed simple non-enzyme glucose biosensor can operate in a linear range of mM– mM and a sensitivity of μA mM −1 cm −2. A detection limit of 9 μM (S/N = 3) was by: 1. Inkjet-printed copper oxide nanoparticles (CuO NPs) on silver electrodes were used to fabricate the nonenzymatic glucose biosensor.

The inkjet-printed CuO NPs electrodes produced high and reproducible sensitivity of μAm M–1 cm–2 at an applied potential of + V with the wide linear-detecting range of – mM and the detection limit of ∼ μM (S/N = 3). Enzymatic and non-enzymatic sensors of silver, gold, and copper nanoparticles are discussed in details in the chapter.

The fabrication of glucose sensors has also been discussed with keeping in view the interest of the researchers. The objective of this chapter is to cover the bare and modified/composites of metal nanoparticles as glucose by: 3.

Keywords:Biosensor, electrocatalysis, electrochemical sensing, glucose, Nano-material, non-enzymatic sensing. Abstract:This overview focuses on the study of non-enzymatic electrochemical glucose sensing over the last decade. The electrocatalytic performances and mechanisms of glucose oxidation using a variety of nanostructured materials are Cited by: 1.

Photoelectrochemical and Non-Enzymatic Glucose Sensor Based on Modified Fehling's Test by Using Ti/TiO 2 NTs-rGO-Cu 2 O Electrode. Journal of The Electrochemical Society(8), BB DOI: / by: @article{osti_, title = {Non-enzymatic glucose sensor based on electrodeposited copper on carbon paste electrode (Cu/CPE)}, author = {Nurani, Dita Arifa, E-mail: @ and Wibowo, Rahmat and Fajri, Iqbal Farhan El}, abstractNote = {The development of non-enzymatic glucose sensor has much attention due to their applications in glucose monitoring.

A novel high-performance non-enzymatic electrochemical sensor was constructed based on the ZIF/CNFs composite. The ZIF/CNFs based sensor exhibited enhanced electrocatalytic activity towards H 2 O 2 compared to a pure ZIFbased sensor, due to the synergistic effects of ZIF and by: 2.

In this work, we report an electrochemical surface plasmon resonance/waveguide (EC-SPR/waveguide) glucose biosensor, which could detect enzymatic reactions in a conducting polymer/glucose oxidase (GO x) multilayer thin order to achieve a controlled enzyme electrode and waveguide mode, GO x (negatively charged) was immobilized with a water Cited by: As a demonstration of its practicality, the Ni-Cu/GO/GCE was used to measure glucose in fetal bovine serum.

Conclusion: A non-enzymatic glucose sensor based on the Ni-Cu/GO/GCE with high sensitivity and improved specificity was developed and characterized.

Selective detection of glucose in a linear concentration range of μM was : Xuming Zhuang and Lingxin Chen. Glycated hemoglobin is an adduct that results from the non-enzymatic reaction of glucose with 10 or electrochemical detection using for the Detection of Total and Glycated Hemoglobin in Cited by: Free-standing, vertically aligned carbon nanotubes (VACNTs) were patterned into 16 µm diameter microchannel arrays for flow-through electrochemical glucose sensing.

Non-enzymatic sensing of glucose was achieved by the chemical reaction of glucose with methyl viologen (MV) at an elevated temperature and pH ( M NaOH), followed by the electrochemical reaction of Cited by: 7. At V, it offered a sensitivity of μA mM–1 cm–2 (one order higher than pure NiO) with a wider linear range from μM to mM, a low detection limit of μM (signal-to-noise ratio = 3, and moreover, good resolution in low glucose concentration, reproducibility, and long-term performance stabi Cited by: enzymatic glucose sensor using electrochemical techniques including cyclic voltammetry and hydrodynamic chronoamperometry.

The results obtained from the amperometric analysis of glucose in a M NaOH solution indicated an e ffi cient performance of the electrode with a low detection limit of. dimensional nanotubular geometry. Herein, a well performing non-enzymatic electrochemical glucose biosensor by using CuO nanoparticle decorated TiO 2 nanotube array electrode was developed.

Well-aligned TiO 2 nanotube arrays were successfully synthesized by. In another case, PtNPs/MnO 2 nanowires/graphene paper used as a free-standing paper electrode for non-enzymatic detection of glucose, the sensor response is linear to the glucose concentrations in the range from to mM with a detection limit of mM (S/N = 3) and detection sensitivity of µA cm −2 mM − by: 4.

Glucose is the most important carbohydrate fuel in the body. In the fed state, the majority of circulating glucose comes from the diet; in the fasting state, gluconeogenesis and glycogenolysis maintain glucose concentrations. Very little glucose is found in the diet as glucose; most is found in more complex carbohydrates that are broken down to monosaccharides though the.

A novel, stable and sensitive non-enzymatic glucose biosensor based on nanocomposites of copper oxide (CuO) and the reduced graphene oxide (rGO) was developed. A facile, green and effective chemical method was employed to synthesize the CuO-rGO nanocomposites in a mixture solution of water-isopropanol.

The nanocomposite is selective for electrochemical hydrogen peroxide (H 2 O 2) reduction and shows a wide linear range (– mmol L −1), low detection limit ( μmol L −1), fast response (less than 5 s), good signal reproducibility (R.S.D. = %), long-term stability (more than one month), plus the low cost.

No interference was. based non-enzymatic glucose detection technique is discussed and, finally, this thesis will be concluded with a discussion of future trends in the development of advanced non-enzymatic glucose sensors.

Mechanism of Metal Oxide Based Glucose Sensor Metal Oxide Molecules Attacked by Hydroxide IonsAuthor: Qiuchen Dong. The development of non-enzymatic glucose sensor has much attention due to their applications in glucose monitoring. In this research, copper oxide is used as a non-enzymatic glucose sensor by oxidizing glucose to gluconolactone.

Copper was electrodeposited on Carbon paste electrode (CPE) at constant potential. The experimental condition was varied in Author: Dita Arifa Nurani, Rahmat Wibowo, Iqbal Farhan El Fajri.

(), “Non enzymatic electrochemical detection of glucose at rice starch-nanoparticles modified electrode”, International Journal of Pharma and Bio Sciences, V. 4, pp. Monica. Gougis M, Tabet-Aoul A, Ma D, Mohamedi M.

Laser synthesis and tailor-design of nanosized gold onto carbon nanotubes for non-enzymatic electrochemical glucose sensor. Sensor. Actuator. B, – [75] Ensafi AA, Abarghoui MM, Rezaei B.

A new non-enzymatic glucose sensor based on copper/porous silicon nanocomposite. Electrochim. HbA1c is a stable glycated hemoglobin derivative formed by the non-enzymatic reaction of glucose with the N-terminal valine of the β-chain of normal adult Hb (HbA).

Since it reflects the average blood glucose level over the preceding 2–3 months and is not affected by the daily fluctuation of the glucose level, the HbA1c level provides a more Cited by: 4.

The developed wireless system included electrochemical analysis circuits, a microcontroller unit, and a wireless communication module. Finally, we evaluated the continuous glucose monitoring system through two animal testing, by implanting into subcutaneous tissue and measuring interstitial fluid (ISF) glucose values at 5–min intervals.

We present a proof-of-concept demonstration of an all-printed temporary tattoo-based glucose sensor for noninvasive glycemic monitoring.

The sensor represents the first example of an easy-to-wear flexible tattoo-based epidermal diagnostic device combining reverse iontophoretic extraction of interstitial glucose and an enzyme-based amperometric biosensor.

Therefore, there is a need to have non-enzymatic glucose sensors that are reproducible, stable and sensitive. Above all, their production should be cost-effective. Copper oxide, a semiconductor material with a narrow band gap, is applied in photovoltaic devices, gas sensing, heterogeneous catalyst, and in glucose sensing.

Graphical abstract: Highlights: • First report on decorating MoS{sub 2} nanosheet with Cu nanoparticles by chemical reduction. • Cu nanoparticles were uniformly decorated on MoS{sub 2} nanosheet. • Glucose biosensor based on copper nanoparticles-MoS{sub 2} nanosheet hybrid is Author: Huang, Jingwei.

Multilayer Nickel–Copper Anode for Direct Glucose Fuel Cell Non-Enzymatic, Glucose Fuel Cells,” Sci. Rep., 3, Google Scholar. Crossref. HPLC Analysis of Carbohydrates With Electrochemical Detection at a Poly Cited by: 2. Linear sweep voltammeric measurement of glucose at the chemical modified electrode indicated that the oxidative peak currents of glucose were linear to its concentration ranging from × to × molL-1 with the detection limits of × molL The direct electrochemistry of glucose was also studied by cyclic voltammetry.

The. PF15 Aruna Ivaturi Non-invasive Non-Enzymatic Electrochemical Glucose Sensors based on Metal Oxide Nanostructures PF16 Caoimhe Robinson Label-free Electrochemical Immunosensor for the Detection of IgG in Calf Serum Corrosion Science C1 Koushik Bangalore Gangadharacharya Thin electrolyte thickness measurements for atmospheric.

CuO NPs have been previously used for non-enzymatic electrochemical sensing of glucose and other molecules. In this context, we have proposed the use of CuO NPs in novel non-enzymatic electrochemical systems (Figure 9), taking advantage of the interactions of CuO NPs with toxic compounds that in turn generate electrochemical signals related.

The electrode also exhibited a low detection limit of μm (S/N=3), good selectivity and reproducibility, and excellent stability during the long-term electrochemical detection.

A stable and sensitive non-enzymatic glucose sensor prepared by modifying a boron-doped diamond electrode with nickel nanosheets and nanodiamonds has been reported Cited by: (52) T. H. Vignesh Kumar and Ashok K. Sundramoorthy*, Non-Enzymatic Electrochemical Detection of Urea on Silver Nanoparticles Anchored Nitrogen-Doped Single-Walled Carbon Nanotube Modified Electrode, J.

Electrochem. Soc. () BB [IF: ].Patents, book chapters, or book serials were omitted for this review. Applications, including electronic tongues and noses, are not covered here either to give more room for fundamental advances. Today, electrochemical sensors are tightly integrated and hyphenated with sampling, fluidic handling, separation, and other detection principles.

49918 views Tuesday, November 24, 2020